Vyne Therapeutics INC

Market Movers (8-K)

NASDAQ
Yarrow Bioscience, Inc. announced an exchange of common stock for pre-funded warrants, impacting outstanding share counts and ownership limitations.
NASDAQ
Yarrow Bioscience, Inc. (formerly VYNE Therapeutics Inc.) announced the closing of its merger with Yarrow Bioscience, Inc. and the commencement of dosing in a Phase 2a/2b trial for YB-101, a potential treatment for Graves' disease and thyroid eye disease.
Capital raise
NASDAQ
VYNE Therapeutics is implementing a 1-for-50 reverse stock split and a special cash dividend in preparation for its merger with Yarrow Bioscience, Inc.
NASDAQ
VYNE Therapeutics and Yarrow Bioscience have released an investor presentation detailing their proposed merger and Yarrow's lead drug candidate, YB-101, for Graves' Disease and Thyroid Eye Disease.
Capital raise
NASDAQ
VYNE Therapeutics announced a special cash dividend of an estimated $16.5 million, or $0.38 per share, in connection with its proposed merger with Yarrow Bioscience.
NASDAQ
Yarrow Bioscience unveils its lead drug candidate, YB-101, an anti-TSHR antibody, highlighting its potential in Graves' Disease and Thyroid Eye Disease, with Phase 2 trials planned and significant funding secured.
Capital raise

Quarterly Earnings (10-Q)

NASDAQ
VYNE Therapeutics reported a reduced net loss for Q3 2025, but terminated its Phase 2b repibresib trial for vitiligo and faces a partial clinical hold on VYN202, prompting a strategic review and cost reductions.
Worse than expected
Capital raise
Delay expected
NASDAQ
VYNE Therapeutics reported mixed clinical trial results for VYN202 and repibresib, leading to trial terminations, while implementing cost reductions to extend its cash runway into the first half of 2027.
Worse than expected
Delay expected
Capital raise
NASDAQ
VYNE Therapeutics announces its Q1 2025 financial results, including a net loss of $8.6 million, and reports a clinical hold on its Phase 1b trial of VYN202 due to testicular toxicity observed in preclinical studies.
Delay expected
Worse than expected
Capital raise
NASDAQ
VYNE Therapeutics reported a net loss of $12.16 million for the third quarter of 2024, with increased research and development expenses due to ongoing clinical trials.
Worse than expected
Capital raise
NASDAQ
VYNE Therapeutics reported a net loss of $15.7 million for the first half of 2024, while advancing its clinical programs for VYN201 and VYN202.
Capital raise
NASDAQ
VYNE Therapeutics reported a net loss of $6.2 million for the first quarter of 2024, while advancing its clinical programs for immuno-inflammatory conditions.
Capital raise

Annual Reports (10-K)

NASDAQ
VYNE Therapeutics announced a definitive merger agreement with Yarrow Biosciences, shifting its strategic focus to Yarrow's clinical-stage TSHR antibody for Graves Disease, following setbacks in its BET inhibitor programs.
Worse than expected
Capital raise
Delay expected
NASDAQ
VYNE Therapeutics' 10-K filing summarizes the company's financial performance for 2024 and provides updates on its clinical development programs, including repibresib gel and VYN202.
Worse than expected
Capital raise
NASDAQ
VYNE Therapeutics Inc. reports its 2023 financial results and provides updates on its clinical-stage immuno-inflammatory drug development programs, including VYN201 and VYN202.
Worse than expected
Delay expected
Capital raise

Insider Trading (Form 4)

NASDAQ
RTW Fund Group GP, LLC and 1 other reported changes in beneficial ownership of VYNE Therapeutics Inc. common stock on July 29, 2026.
NASDAQ
Mona Ashiya, a Director of VYNE Therapeutics Inc., received 15,435 shares of common stock on July 27, 2026.
NASDAQ
Tyler Zeronda, a Director of VYNE Therapeutics Inc., received 185,798 shares of common stock on July 27, 2026.
NASDAQ
Tyler Zeronda, CHIEF FINANCIAL OFFICER of VYNE Therapeutics Inc., reported a transaction in 22,516 shares of common stock on July 23, 2026.
NASDAQ
Iain Stuart, CHIEF SCIENTIFIC OFFICER of VYNE Therapeutics Inc., reported a transaction in 15,405 shares of common stock on July 23, 2026.
NASDAQ
Mutya Harsch, CHIEF LEGAL OFFICER AND GC of VYNE Therapeutics Inc., reported a transaction in 22,516 shares of common stock on July 23, 2026.

Proxy Statements (Def-14A)

NASDAQ
VYNE Therapeutics Inc. announces its 2025 Annual Meeting of Stockholders to vote on director elections, auditor ratification, and executive compensation, while revealing increasing net losses and a recent Phase 2b trial failure.
Delay expected
Capital raise
Worse than expected
NASDAQ
VYNE Therapeutics is holding its annual meeting on December 12, 2024, to vote on key proposals including the election of directors, ratification of the auditor, executive compensation, and an amendment to the equity incentive plan.

Schedule 13D - Activist Investments

NASDAQ
AI Biotechnology LLC and affiliated entities report a 6.02% stake in Yarrow Bioscience, Inc. following a merger and stock split.

Schedule 13G - Passive Investments

NASDAQ
Perceptive Advisors LLC, Joseph Edelman, and Perceptive Life Sciences Master Fund, Ltd. have jointly filed a Schedule 13G, reporting beneficial ownership of 9.99% of Yarrow Bioscience, Inc.'s common stock.
NASDAQ
RTW Fund Group GP, LLC and Roderick Wong, M.D. have reported beneficial ownership of 9.99% of Yarrow Bioscience, Inc. common stock.
NASDAQ
Zhang Xiaofan has filed a Schedule 13G, reporting beneficial ownership of 16.5% of VYNE Therapeutics Inc. common stock.
NASDAQ
Zhang Xiaofan has reported beneficial ownership of 4,595,118 shares, representing 13.8% of VYNE Therapeutics Inc.'s common stock, as of July 13, 2026.
NASDAQ
Zhang Xiaofan has reported beneficial ownership of 1,873,388 shares, representing 5.6% of the outstanding common stock of VYNE Therapeutics Inc.
NASDAQ
Nantahala Capital Management, LLC has reported a 6% beneficial ownership stake in VYNE Therapeutics Inc. as of March 31, 2026.