Regulus Therapeutics INC
Market Movers (8-K)
Regulus Therapeutics Inc. has been acquired by Novartis AG's indirect wholly-owned subsidiary, Redwood Merger Sub Inc., for $7.00 per share in cash plus a contingent value right, following a successful tender offer.
8-K: Novartis to Acquire Regulus Therapeutics for Up to $1.7 Billion, Boosting ADPKD Treatment Pipeline
Regulus Therapeutics announces acquisition by Novartis for $7.00 per share in cash, with a potential additional $7.00 per share via a contingent value right, alongside positive Phase 1b data for farabursen in ADPKD.
Better than expected
Novartis AG will acquire Regulus Therapeutics for $7.00 per share in cash, plus a contingent value right (CVR) of up to $7.00 per share, potentially valuing the company at approximately $1.7 billion.
Better than expected
8-K: Regulus Therapeutics Announces Positive Topline Results from Phase 1b Study of Farabursen for ADPKD
Regulus Therapeutics reports positive topline results from the fourth cohort of its Phase 1b study of farabursen (RGLS8429) for autosomal dominant polycystic kidney disease (ADPKD), showing a halting of kidney volume growth.
Better than expected
Regulus Therapeutics reported positive interim results from a Phase 1b trial of farabursen for ADPKD and alignment with the FDA on a Phase 3 trial design, along with its year-end 2024 financial results.
Better than expected
Regulus Therapeutics extends its lease agreement for its San Diego facility, ensuring continued operations at its current location until April 2028.
Quarterly Earnings (10-Q)
Regulus Therapeutics reports Q1 2025 results, highlighting ongoing losses and liquidity concerns despite a pending acquisition by Novartis.
Worse than expected
Capital raise
10-Q: Regulus Therapeutics Reports Third Quarter 2024 Financial Results and Provides Clinical Update
Regulus Therapeutics Inc. has released its financial results for the third quarter of 2024, alongside updates on its clinical programs, particularly RGLS8429 for ADPKD.
Worse than expected
Capital raise
10-Q: Regulus Therapeutics Reports Second Quarter 2024 Financial Results and Provides Business Update
Regulus Therapeutics reported a net loss of $11.0 million for the second quarter of 2024, while highlighting progress in its RGLS8429 clinical trial for ADPKD.
Worse than expected
Capital raise
10-Q: Regulus Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Update
Regulus Therapeutics reported a net loss of $8.5 million for the first quarter of 2024, while highlighting progress in its RGLS8429 clinical trial for ADPKD.
Worse than expected
Capital raise
Annual Reports (10-K)
Regulus Therapeutics files an amendment to its annual report on Form 10-K to include information required in Part III, which was not initially included due to the delay in filing the definitive proxy statement.
Delay expected
Capital raise
Regulus Therapeutics advances farabursen clinical development for ADPKD while navigating financial uncertainties.
Worse than expected
Capital raise
Regulus Therapeutics Inc. has filed its annual 10-K report, disclosing executive salary increases and providing an overview of its financial status and clinical development programs.
Worse than expected
Delay expected
Capital raise
Insider Trading (Form 4)
Regulus Therapeutics Inc. director William H. Rastetter has disposed of his common stock and derivative securities as the company completed its merger, becoming a wholly-owned subsidiary of Novartis AG.
Pascale Witz, a Director of Regulus Therapeutics Inc., has reported the disposition of all her beneficial ownership in the company's securities, effective June 25, 2025, due to the completion of the merger with Novartis AG.
Regulus Therapeutics Inc. has been acquired by Redwood Merger Sub Inc., a Novartis AG subsidiary, resulting in the disposition of all common stock, options, and warrants held by Director Stelios Papadopoulos in exchange for cash and contingent value rights.
A recent SEC Form 4 filing reveals that Hugh Rosen, a Director at Regulus Therapeutics Inc., has disposed of all his common stock, restricted stock units, and stock options as a result of the company's acquisition by Novartis AG.
Form 4: Regulus Therapeutics Insider Disposes All Holdings Following Novartis Acquisition Completion
Preston Klassen, President and Head of R&D at Regulus Therapeutics Inc., has disposed of all his common stock, performance stock units, and stock options following the completion of the company's acquisition by Novartis AG.
A senior executive at Regulus Therapeutics Inc. has filed a Form 4 detailing the conversion of his equity holdings into cash and contingent value rights as a result of the company's acquisition by Novartis AG.
Proxy Statements (Def-14A)
Regulus Therapeutics amends its proxy statement to include details about its engagement with Alliance Advisors LLC for proxy solicitation.
Regulus Therapeutics is holding its annual meeting on May 16, 2024, to vote on director elections, executive compensation, auditor ratification, and an amendment to the equity incentive plan.
Schedule 13G - Passive Investments
Point72 Asset Management, Point72 Capital Advisors, and Steven A. Cohen collectively reported a 0.3% beneficial ownership stake in Regulus Therapeutics Inc., primarily through warrants.
Deep Track Capital and its affiliates have fully divested their beneficial ownership in Regulus Therapeutics Inc., reporting 0% stake.
Worse than expected
Vivo Opportunity Fund Holdings, L.P. and its general partner, Vivo Opportunity, LLC, have filed an amended Schedule 13G, disclosing a 3.9% passive beneficial ownership in Regulus Therapeutics Inc.
Point72 Asset Management, along with its affiliates and founder Steven A. Cohen, has disclosed a passive 5.9% beneficial ownership stake in Regulus Therapeutics Inc., including shares issuable from warrants.
Better than expected
Capital raise