Orchestra Biomed Holdings, INC

Market Movers (8-K)

NASDAQ
Orchestra BioMed Holdings, Inc. announced new executive compensation plans, including a cash bonus program tied to clinical trial milestones and financial objectives, alongside revised RSU vesting and salary increases for its CEO and COO.
NASDAQ
Orchestra BioMed expects to receive up to $21 million in proceeds from the acquisition of its strategic holding, Vivasure Medical, by Haemonetics Corporation.
Better than expected
NASDAQ
Orchestra BioMed Holdings, Inc. announced significant strategic financing totaling nearly $150 million and provided updates on its pivotal AVIM Therapy and Virtue SAB clinical trials.
Better than expected
Capital raise
Delay expected
NASDAQ
Orchestra BioMed Holdings, Inc. highlights its pivotal-stage therapies, strategic partnerships, and over $147 million in new capital commitments to fund operations into Q4 2027.
Better than expected
Capital raise
NASDAQ
Orchestra BioMed has entered new strategic agreements with Terumo, securing $30 million in funding and initiating its pivotal U.S. Virtue SAB clinical trial for coronary in-stent restenosis.
Capital raise
Better than expected
NASDAQ
Orchestra BioMed Holdings, Inc. successfully completed a public offering and private placement, raising approximately $56.2 million to advance its AVIM therapy and Virtue SAB programs.
Capital raise

Quarterly Earnings (10-Q)

NASDAQ
Orchestra BioMed reports increased net losses in Q3 2025, but secures significant new financing and initiates a pivotal clinical trial for Virtue SAB, while terminating its Terumo agreement.
Worse than expected
Delay expected
Capital raise
NASDAQ
Orchestra BioMed Holdings, Inc. reported increased Q2 losses and R&D expenses but secured $76.2 million in new capital and extended debt amortization, providing funding into late 2027.
Delay expected
Worse than expected
Capital raise
NASDAQ
Orchestra BioMed Holdings reports increased revenue but a larger net loss in Q1 2025, while also expressing substantial doubt about its ability to continue as a going concern due to insufficient capital.
Delay expected
Worse than expected
Capital raise
NASDAQ
Orchestra BioMed Holdings announced its Q3 2024 financial results, highlighting a revenue increase and a new $50 million loan facility, while also noting ongoing research and development expenses.
Worse than expected
Delay expected
Capital raise
NASDAQ
Orchestra BioMed Holdings reported a net loss of $29.4 million for the first six months of 2024, with ongoing investments in research and development.
Worse than expected
Delay expected
Capital raise
NASDAQ
Orchestra BioMed Holdings reported a net loss of $13.5 million for the first quarter of 2024, while highlighting advancements in its BackBeat CNT and Virtue SAB programs.
Worse than expected
Delay expected
Capital raise

Annual Reports (10-K)

NASDAQ
Orchestra BioMed Holdings, Inc. reported a net loss of $52.7 million for 2025, while advancing key clinical trials for its AVIM Therapy and Virtue SAB product candidates and securing new financing.
Delay expected
Capital raise
NASDAQ
Orchestra BioMed Holdings details its 2024 financial performance, highlighting progress in clinical trials and strategic partnerships amid ongoing financial challenges.
Worse than expected
Delay expected
Capital raise
NASDAQ
Orchestra BioMed's 10-K filing details its authorized and outstanding stock, warrants, registration rights, and corporate governance, providing a comprehensive overview of its securities structure.
Delay expected
Capital raise

Insider Trading (Form 4)

NASDAQ
Orchestra BioMed Holdings, Inc. reports a Form 4 filing detailing stock transactions by Director Eric S. Fain, including RSU awards and share withholding for tax obligations.
NASDAQ
David Pacitti, a Director at Orchestra BioMed Holdings, Inc., acquired restricted stock units and stock options on June 23, 2026, as part of his compensation.
NASDAQ
Orchestra BioMed Holdings, Inc. director Chris Cleary acquired stock options and had shares withheld for tax obligations related to RSU vesting.
NASDAQ
Orchestra BioMed Holdings, Inc. reports that Director Pamela Ann Connealy was granted restricted stock units and stock options on June 23, 2026.
NASDAQ
Orchestra BioMed Holdings, Inc. director Aryeh Jason was granted stock options for 42,553 shares.
NASDAQ
Orchestra BioMed Holdings, Inc. Director John Prosper Mack reported transactions involving restricted stock units and common stock.

Proxy Statements (Def-14A)

NASDAQ
Orchestra BioMed Holdings, Inc. announces its 2025 Annual Meeting of Stockholders to be held virtually on June 24, 2025, with voting matters including the election of directors and ratification of the company's independent auditor.
NASDAQ
Orchestra BioMed Holdings will hold its 2025 Annual Meeting of Stockholders virtually on June 24, 2025, to elect directors and ratify the appointment of its independent accounting firm.
NASDAQ
Orchestra BioMed Holdings, Inc. will hold its annual meeting on June 20, 2024, and is soliciting votes on the election of directors and ratification of its accounting firm.
NASDAQ
Orchestra BioMed Holdings will hold its 2024 Annual Meeting of Stockholders virtually on June 20, 2024, to elect directors and ratify the appointment of Ernst & Young LLP as its independent accounting firm.

Schedule 13D - Activist Investments

NASDAQ
RTW Investments, LP and affiliated funds have increased their beneficial ownership in Orchestra Biomed Holdings, Inc. to 19.2% following the cashless exercise of pre-funded warrants.
NASDAQ
RTW Investments and its affiliated funds have increased their beneficial ownership in Orchestra BioMed Holdings, Inc. to 19.7% by raising the maximum percentage under pre-funded warrants.
NASDAQ
RTW Investments and its affiliated funds increased their beneficial ownership in Orchestra BioMed Holdings, Inc. to 15.4% through the purchase of pre-funded warrants in a public offering.
Capital raise
Delay expected
NASDAQ
RTW Investments, LP and its affiliated funds have increased their beneficial ownership in Orchestra Biomed Holdings, Inc. to 21.7% through recent open market purchases.

Schedule 13G - Passive Investments

NASDAQ
Medtronic plc and Covidien Group S.a.r.l. have jointly reported a beneficial ownership of 17.8% in Orchestra BioMed Holdings, Inc. common stock.
NASDAQ
Tasso Partners, LLC and Dana Lorenzo have jointly filed a Schedule 13G, disclosing beneficial ownership of 5.5% of Orchestra BioMed Holdings, Inc.'s common stock.
NASDAQ
Perceptive Advisors, Joseph Edelman, and Perceptive Life Sciences Master Fund collectively reported a 9.99% beneficial ownership stake in Orchestra BioMed Holdings, Inc.
NASDAQ
BlackRock, Inc. has filed an amended Schedule 13G, reporting a 3.7% passive beneficial ownership stake in Orchestra BioMed Holdings, Inc. as of March 31, 2025.
NASDAQ
Medtronic plc and its subsidiary Covidien Group S.a.r.l. have disclosed a combined beneficial ownership of 15.4% in Orchestra BioMed Holdings, Inc., holding 5,868,916 shares of common stock as of December 31, 2024.