Opus Genetics, INC
Market Movers (8-K)
NASDAQ
Opus Genetics highlighted its expanding gene therapy pipeline for inherited retinal diseases (IRDs), with five programs targeting significant unmet needs and multiple clinical data readouts expected.
NASDAQ
Opus Genetics provided an update on its gene therapy pipeline, highlighting progress in five Inherited Retinal Disease (IRD) programs and outlining upcoming clinical milestones.
NASDAQ
Opus Genetics announced Q1 2026 financial results, highlighting progress in gene therapy programs for inherited retinal diseases and an extended cash runway into 2029.
Worse than expected
Capital raise
NASDAQ
Opus Genetics, Inc. has successfully closed an initial $35 million tranche of a $155 million senior secured note facility.
Capital raise
NASDAQ
Opus Genetics, Inc. held its 2026 annual meeting, where stockholders elected directors, ratified auditor appointment, approved executive compensation, and authorized a stock increase.
Capital raise
NASDAQ
Opus Genetics has entered into agreements to reimburse top executives for excise taxes triggered by a potential change in control of the company.
Quarterly Earnings (10-Q)
NASDAQ
Opus Genetics reports a significant increase in R&D expenses for its inherited retinal disease pipeline, alongside a substantial swing in warrant liability fair value, impacting net loss for the first quarter of 2026.
Worse than expected
Capital raise
NASDAQ
Opus Genetics reported a significantly wider net loss in Q3 2025, driven by warrant liability changes and increased R&D for gene therapies, while securing new capital to advance its pipeline.
Delay expected
Worse than expected
Capital raise
NASDAQ
Opus Genetics reports increased cash reserves and significant progress in its gene therapy pipeline, despite rising operating expenses and continued net losses.
Capital raise
NASDAQ
Opus Genetics reports its financial results for the first quarter of 2025, highlighting revenue from the Viatris license agreement and progress in its gene therapy programs.
Worse than expected
NASDAQ
Opus Genetics, formerly Ocuphire Pharma, has completed a merger, shifting its focus to gene therapies for inherited retinal diseases while advancing its existing ophthalmic programs.
Worse than expected
Capital raise
NASDAQ
Ocuphire Pharma reports a net loss of $14.9 million for the first six months of 2024, while continuing to advance its pipeline of ophthalmic therapies.
Worse than expected
Capital raise
Annual Reports (10-K)
NASDAQ
Opus Genetics, a clinical-stage biopharmaceutical company, reported positive clinical trial results for its lead gene therapies, OPGx-LCA5 and OPGx-BEST1, alongside reduced net losses and increased cash reserves for fiscal year 2025.
Capital raise
Better than expected
NASDAQ
Opus Genetics provides an update on its financial standing, gene therapy pipeline advancements, and strategic partnerships in its annual 10-K filing.
Capital raise
Worse than expected
NASDAQ
10-K: Ocuphire Pharma Releases 2023 Annual Report, Highlights Progress in Retinal and Refractive Therapies
Ocuphire Pharma's 2023 annual report details the company's progress in developing novel therapies for retinal and refractive eye disorders, including the FDA approval of RYZUMVI and advancements in clinical trials for APX3330 and PS.
Worse than expected
Capital raise
Insider Trading (Form 4)
NASDAQ
Benjamin R Yerxa, President and a Director of Opus Genetics, Inc., sold 7,429 shares of common stock on July 23, 2026 for $2.97 per share.
NASDAQ
Form 4: Opus Genetics COO Sells Shares
Joseph K Schachle, Chief Operating Officer of Opus Genetics, Inc., sold 4,644 shares of common stock on July 23, 2026 for $2.94 per share.
NASDAQ
Form 4: Opus Genetics CEO Sells Shares
George Magrath, Chief Executive Officer and a Director of Opus Genetics, Inc., sold 9,475 shares of common stock on July 23, 2026 for $2.95 per share.
NASDAQ
Form 4: Opus Genetics CFO Sells Shares
Robert E. Gagnon, Chief Financial Officer of Opus Genetics, Inc., sold 7,783 shares of common stock on July 23, 2026 for $2.95 per share.
NASDAQ
Foundation Fighting Blindness Retinal Degeneration Fund sold 1.7 million shares of Opus Genetics, Inc. at $4.35 per share.
NASDAQ
Benjamin R. Yerxa, President of Opus Genetics, sold 7,470 shares to satisfy tax withholding obligations related to RSU vesting.
Proxy Statements (Def-14A)
NASDAQ
Opus Genetics, Inc. is calling its 2026 Annual Meeting of Stockholders to vote on key proposals including the election of directors, executive compensation, and a significant increase in authorized common stock to support future growth and financing needs.
Capital raise
NASDAQ
Opus Genetics, Inc. has filed a definitive proxy statement with the Securities and Exchange Commission.
NASDAQ
Opus Genetics will hold its annual meeting of stockholders virtually on April 30, 2025, to vote on director elections, auditor ratification, executive compensation, preferred stock conversion, and meeting adjournment.
NASDAQ
DEFA14A: Opus Genetics Amends Proxy Statement Following Withdrawal of Director Nominees by Sooch Group
Opus Genetics updates its proxy statement after the Sooch Group withdraws its director nominees for the upcoming annual meeting.
NASDAQ
DEFA14A: Opus Genetics Urges Stockholders to Vote FOR Board Nominees Amidst Contentious Proxy Battle
Opus Genetics files its definitive proxy statement and urges stockholders to vote for its board nominees, highlighting the company's transformation and progress while criticizing a campaign by former CEO Mina Sooch to replace a majority of directors.
NASDAQ
DEFC14A: Opus Genetics Faces Proxy Battle as Sooch Group Challenges Board at Upcoming Annual Meeting
Opus Genetics is urging shareholders to vote for its director nominees amidst a proxy fight initiated by a stockholder group led by former CEO Mina Sooch.
Capital raise
Schedule 13D - Activist Investments
NASDAQ
Foundation Fighting Blindness RD Fund and Foundation Fighting Blindness, Inc. have reduced their stake in Opus Genetics, Inc. below the 5% reporting threshold.
NASDAQ
Foundation Fighting Blindness entities have reduced their beneficial ownership in Opus Genetics, Inc. to 8.0% following a share sale on December 9, 2025.
NASDAQ
SCHEDULE 13D/A: Foundation Fighting Blindness Entities Increase Stake in Opus Genetics to 15.9% Following Preferred Stock Conversion
Foundation Fighting Blindness Retinal Degeneration Fund and Foundation Fight Blindness, Inc. have increased their beneficial ownership in Opus Genetics, Inc. to 15.9% of common stock following the automatic conversion of preferred shares.
Schedule 13G - Passive Investments
NASDAQ
Perceptive Advisors and Joseph Edelman have filed a Schedule 13G reporting a 9.99% beneficial ownership stake in Opus Genetics, Inc.
NASDAQ
Caligan Partners LP and David Johnson have reported beneficial ownership of 8.5% of Opus Genetics, Inc. common stock as of March 31, 2026.
NASDAQ
Balyasny Asset Management L.P. and affiliated entities have reported beneficial ownership of 7.18% of Opus Genetics Inc. common stock as of March 31, 2026.
NASDAQ
Several Bios-affiliated entities and individuals have reported a combined beneficial ownership of 4.53% in Opus Genetics, Inc. common stock.
NASDAQ
Adage Capital Management, L.P., along with individuals Robert Atchinson and Phillip Gross, has filed a Schedule 13G, reporting beneficial ownership of 8.47% of Opus Genetics, Inc. common stock as of March 31, 2026.
NASDAQ
Balyasny Asset Management and its affiliates have reported a 7.41% beneficial ownership stake in Opus Genetics Inc., totaling 5,110,373 shares.