Stockholders approved the Amended and Restated 2021 Equity Incentive Plan. The amendment revises the 'Evergreen Provision' to include shares issuable upon exercise of pre-funded warrants in the calculation of the annual share reserve increase. The plan now provides for full vesting of unvested time-based awards upon an employee's death. Stockholders elected Andrew Levin, M.D., Ph.D. and Fouad Namouni, M.D. as Class II directors. Ernst & Young LLP was ratified as the independent registered public accounting firm for 2026.