SCHEDULE: FMR LLC Reports Stake in Uniqure N.V.

FMR LLC and Abigail P. Johnson have filed a Schedule 13G, reporting beneficial ownership of 2.8% of Uniqure N.V.'s common stock as of March 31, 2026.

Summary

• FMR LLC and Abigail P. Johnson have jointly filed a Schedule 13G, indicating their beneficial ownership of Uniqure N.V. common stock.
• As of March 31, 2026, the total number of shares beneficially owned is 1,743,807.87.
• This represents 2.8% of the total outstanding common stock of Uniqure N.V.
• FMR LLC is classified as a holding company (HC), and Abigail P. Johnson is classified as an investment company (IN).
• The filing confirms that the securities were acquired and are held in the ordinary course of business and not for the purpose of influencing control of the issuer.

Sentiment

Score: 5

Explanation: StockSavvy.ai views this as a neutral filing, as it is a routine disclosure of beneficial ownership and does not contain operational or financial performance data for Uniqure N.V.

Positives

• FMR LLC and Abigail P. Johnson maintain a significant stake, representing 2.8% of Uniqure N.V.'s common stock.
• The filing indicates that the shares are held in the ordinary course of business, suggesting a standard investment approach rather than a hostile takeover attempt.

Risks

• While not explicitly stated as a risk in this filing, any significant change in the beneficial ownership reported by FMR LLC or Abigail P. Johnson could impact Uniqure N.V.'s stock price.
• The filing does not provide details on the specific investment strategy or rationale behind acquiring this stake, which could be a point of interest for other investors.

Future Outlook

This filing is a disclosure of beneficial ownership and does not contain forward-looking statements or guidance regarding Uniqure N.V.'s future performance.

Management Comments

• "By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11."
• "FMR LLC By /s/ Richard Bourgelas Richard Bourgelas Duly authorized under Power of Attorney effective as of April 13, 2026, by and on behalf of FMR LLC and its direct and indirect subsidiaries*"
• "Abigail P. Johnson By /s/ Richard Bourgelas Richard Bourgelas Duly authorized under Power of Attorney effective as of April 13, 2026, by and on behalf of Abigail P. Johnson*"

Industry Context

StockSavvy.ai notes that Schedule 13G filings are common for institutional investors and investment management firms like FMR LLC to report significant passive stakes in publicly traded companies. This filing indicates FMR LLC's continued interest in the biotechnology or gene therapy sector where Uniqure N.V. operates.

Stakeholder Impact

• Shareholders: The filing provides transparency regarding significant institutional ownership, which can influence market perception.
• Management of Uniqure N.V.: Awareness of FMR LLC's stake may inform strategic discussions, though the passive nature of the filing suggests no immediate intent to influence control.
• Competitors: This filing does not directly impact competitors but contributes to the overall understanding of investment activity in the gene therapy sector.

Next Steps

• FMR LLC and Abigail P. Johnson will continue to hold their reported stake in Uniqure N.V.
• Future filings will be made if their beneficial ownership changes significantly.

Key Dates

Keywords

Uniqure N.V., FMR LLC, Abigail P. Johnson, Schedule 13G, Beneficial Ownership, Common Stock, SEC Filing, Investment, Holding Company, Investment Company