SCHEDULE 13G/A: Frazier Life Sciences Funds Disclose Over 10% Stake in Trevi Therapeutics

Sentiment:

Beneficial Ownership Report (Schedule 13G Amendment)


Frazier Life Sciences Public Fund, L.P. and affiliated entities, along with key individuals, have filed an amended Schedule 13G disclosing a combined beneficial ownership of 10.6% in Trevi Therapeutics, Inc.

Summary

  • Frazier Life Sciences Public Fund, L.P. and its related entities (FHMLSP, L.P. and FHMLSP, L.L.C.) beneficially own 8,508,021 shares, representing 8.8% of Trevi Therapeutics, Inc. common stock.
  • Frazier Life Sciences X, L.P. and its related entities (FHMLS X, L.P. and FHMLS X, L.L.C.) beneficially own 397,309 shares, representing 0.4% of Trevi Therapeutics, Inc. common stock.
  • Frazier Life Sciences XI, L.P. and its related entities (FHMLS XI, L.P. and FHMLS XI, L.L.C.) beneficially own 1,354,079 shares, representing 1.4% of Trevi Therapeutics, Inc. common stock.
  • Key individuals James N. Topper and Patrick J. Heron each beneficially own an aggregate of 10,259,409 shares, representing 10.6% of the outstanding common stock, through their shared voting and investment power over the combined holdings of the Frazier Life Sciences funds.
  • Albert Cha and James Brush each beneficially own 8,508,021 shares (8.8%) through their shared voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P.
  • Daniel Estes beneficially owns 1,354,079 shares (1.4%) through his shared voting and investment power over the shares held by Frazier Life Sciences XI, L.P.
  • The percentage ownership is calculated based on 96,682,229 shares of Common Stock outstanding as of March 14, 2025, as reported in Trevi Therapeutics, Inc.'s Annual Report on Form 10-K.

Sentiment

Score: 5

Explanation: The document is a standard beneficial ownership disclosure (Schedule 13G Amendment) and does not contain information that inherently indicates positive or negative sentiment regarding the company's performance or outlook. It merely reports a significant ownership stake.

Positives

  • The filing indicates a significant and continued investment by Frazier Life Sciences, a prominent life sciences fund, which could be interpreted as a vote of confidence in Trevi Therapeutics, Inc.

Future Outlook

NA

Industry Context

NA

Corporate Governance

Change TypeDescriptionEffective DateImpact Assessment

Stakeholder Impact

  • The disclosure of a significant 10.6% ownership stake by Frazier Life Sciences, a reputable life sciences investment group, may be viewed positively by other shareholders as a sign of institutional confidence in Trevi Therapeutics.
  • The potential for the investor group to nominate directors, as indicated by the certification, suggests a future possibility of influencing corporate governance and strategic direction, which could impact existing management and other stakeholders.

Key Dates

DateDescription
March 14, 2025Date of Trevi Therapeutics, Inc.'s Annual Report on Form 10-K, which provided the outstanding share count used for ownership percentage calculation.
March 31, 2025Date of event which required the filing of this Schedule 13G Amendment No. 4.
May 15, 2025Filing date of the Schedule 13G Amendment No. 4.

Recommendation

hold

Keywords

Trevi Therapeutics, Frazier Life Sciences, Beneficial Ownership, Schedule 13G, SEC Filing, Common Stock, Institutional Ownership, Biotech, Pharmaceutical

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