SCHEDULE: State Street Discloses 5.2% Stake in Alkermes PLC

State Street Corporation has reported a 5.2% beneficial ownership stake in Alkermes PLC, holding over 8.5 million common shares as of September 30, 2025.

Summary

• State Street Corporation filed a Schedule 13G, disclosing its beneficial ownership in Alkermes PLC.
• As of September 30, 2025, State Street Corporation beneficially owns 8,540,351 shares of Alkermes PLC common stock.
• This ownership represents 5.2% of the total class of Alkermes PLC securities.
• State Street Corporation holds shared voting power over 8,026,911 shares and shared dispositive power over 8,540,351 shares.
• The shares were acquired and are held in the ordinary course of business, not for the purpose of changing or influencing control of Alkermes PLC.

Sentiment

Score: 6

Explanation: The filing is a routine disclosure of a significant passive institutional ownership. While not directly impacting company performance, it signals a large, established financial institution holds a substantial stake, which can be seen as a vote of confidence. It contains no negative information.

Positives

• A major financial institution, State Street Corporation, holds a significant stake, indicating institutional presence in Alkermes PLC's stock.

Future Outlook

This filing is a routine disclosure of beneficial ownership and does not contain any forward-looking statements or guidance regarding Alkermes PLC's future performance or strategic outlook.

Management Comments

• Elizabeth Schaefer, Senior Vice President, Chief Accounting Officer of State Street Corporation, certified that the securities were acquired and are held in the ordinary course of business and not for the purpose of or with the effect of changing or influencing the control of Alkermes PLC.

Industry Context

This filing represents a standard disclosure of institutional ownership by a major asset manager, State Street Corporation, which manages diversified portfolios for its clients. It reflects the routine investment activities of large financial institutions in publicly traded companies like Alkermes PLC.

Stakeholder Impact

• Shareholders: Provides transparency regarding the significant institutional ownership by State Street Corporation, which may be viewed as a positive signal of institutional interest.
• Company Management: Indicates awareness of a substantial passive shareholder, which is a common aspect of managing a publicly traded company.

Next Steps

• State Street Corporation will file updates to this Schedule 13G if there are significant changes to its beneficial ownership of Alkermes PLC, as required by SEC regulations.

Key Dates

Keywords

Alkermes PLC, State Street Corporation, Schedule 13G, beneficial ownership, institutional investor, common stock, G01767105