Form 4: Spyre Therapeutics Director Sells Shares
Insider Transaction (Form 4)
Jeffrey W. Albers, a Director of Spyre Therapeutics, Inc., sold 23,000 shares of common stock on August 7, 2026.
Summary
- Option exercise/conversion: acquired 5,000 Common Stock at $10.39 ($51,950) on August 7, 2026; holds 5,000 after (Direct).
- Open-market sale: disposed of 5,000 Common Stock at $104.47 ($522,350) on August 7, 2026 (Direct).
- Open-market sale: disposed of 8,000 Common Stock at $104.38 ($835,040) on August 7, 2026; holds 19,360 after (Indirect).
- Open-market sale: disposed of 10,000 Common Stock at $104.68 ($1,046,800) on August 7, 2026; holds 9,360 after (Indirect).
- Option exercise/conversion: disposed of 5,000 Stock Option (Right to Buy) on August 7, 2026; holds 45,000 after (Direct).
Sentiment
Score: 4
Explanation: StockSavvy.ai views this as a mildly negative but low-conviction signal: an insider sold $2,404,190 of stock under a pre-arranged Rule 10b5-1 plan, which is typically routine.
Insider Transactions
Jeffrey W. Albers — Director
Transaction made under a Rule 10b5-1 trading plan.
| Date | Transaction | Security | Shares | Price | Value | Held After |
|---|---|---|---|---|---|---|
| 2026-08-07 | Option exercise/conversion | Common Stock | 5,000 | $10 | $52.0K | 5,000 |
| 2026-08-07 | Open-market sale | Common Stock | 5,000 | $104 | $522.4K | 0 |
| 2026-08-07 | Open-market sale | Common Stock | 8,000 | $104 | $835.0K | 19,360 |
| 2026-08-07 | Open-market sale | Common Stock | 10,000 | $105 | $1.0M | 9,360 |
| 2026-08-07 | Option exercise/conversion | Stock Option (Right to Buy) | 5,000 | — | — | 45,000 |
Key Dates
| Date | Description |
|---|---|
| 2026-08-07 | Option exercise/conversion (5,000 shares) |
| 2026-08-07 | Open-market sale (5,000 shares) |
| 2026-08-07 | Open-market sale (8,000 shares) |
| 2026-08-07 | Open-market sale (10,000 shares) |
| 2026-08-07 | Option exercise/conversion (5,000 shares) |
Keywords
insider transaction, Form 4, SYRE, Spyre Therapeutics, Inc., bearish, Jeffrey W. Albers
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