Form 4: Opaleye Management Increases Sol-Gel Technologies Stake

Opaleye Management Inc., a 10% owner of Sol-Gel Technologies Ltd., reported an acquisition of 2,735 ordinary shares at a weighted average price of $40.3701.

Summary

• Opaleye Management Inc. acquired 2,735 ordinary shares of Sol-Gel Technologies Ltd. (SLGL).
• The transaction occurred on December 17, 2025.
• Shares were purchased at a weighted average price of $40.3701, with individual transaction prices ranging from $38.00 to $40.50.
• Following this acquisition, Opaleye Management Inc. indirectly beneficially owns 374,530 ordinary shares through Opaleye, L.P., and an additional 10,000 shares through a separately managed account.
• The transaction was made pursuant to a Rule 10b5-1(c) contract, instruction, or written plan.

Sentiment

Score: 8

Explanation: The acquisition of additional shares by a 10% owner and investment manager suggests strong confidence in the company's prospects, which is generally a positive signal for investors.

Positives

• A significant shareholder and 10% owner, Opaleye Management Inc., increased its stake in Sol-Gel Technologies Ltd., signaling confidence in the company's future outlook.
• The purchase was executed under a Rule 10b5-1(c) plan, indicating a pre-planned transaction rather than a reactive one.

Negatives

• No explicit negative information is contained within this Form 4 filing, which primarily reports a transaction.

Risks

• No specific risks are detailed in this Form 4 filing, which primarily reports a change in beneficial ownership.

Related Party Transactions

• Opaleye Management Inc., a 10% owner of Sol-Gel Technologies Ltd., acquired additional shares, which is considered a related party transaction due to its significant ownership and potential influence.

Stakeholder Impact

• Shareholders may view the increased stake by a significant owner as a positive indicator of the company's value and future performance, potentially boosting investor confidence.

Key Dates

Recommendation

The purchase of additional shares by a 10% owner and investment manager, Opaleye Management Inc., signals strong insider confidence in Sol-Gel Technologies Ltd.'s valuation and future prospects. Such insider buying often precedes positive company developments or reflects a belief that the stock is undervalued, making it a 'buy' signal for seasoned investors.

Keywords

Sol-Gel Technologies, SLGL, Opaleye Management, Insider Buying, Form 4, Beneficial Ownership, Equity Acquisition, 10% Owner, Rule 10b5-1