Form 4: Opaleye Management Boosts Sol-Gel Stake

Opaleye Management Inc., a 10% owner and director, increased its beneficial ownership in Sol-Gel Technologies Ltd. by purchasing 5,784 ordinary shares.

Summary

• Opaleye Management Inc., a 10% owner and director of Sol-Gel Technologies Ltd. (SLGL), acquired additional shares.
• On November 20, 2025, Opaleye Management Inc. purchased 5,784 ordinary shares of Sol-Gel Technologies Ltd.
• The shares were acquired at a weighted average price of $35.8305 per share, with prices ranging from $35.132 to $36.10.
• The transaction was made pursuant to a Rule 10b5-1(c) plan, indicating a pre-arranged purchase.
• Following this transaction, Opaleye Management Inc. beneficially owns a total of 373,151 ordinary shares indirectly through Opaleye, L.P. (363,151 shares) and a separately managed account (10,000 shares).

Sentiment

Score: 7

Explanation: The purchase of additional shares by a 10% owner and director suggests confidence in the company's valuation and future performance, which is a positive indicator for investors.

Positives

• A 10% owner and director, Opaleye Management Inc., increased its stake in Sol-Gel Technologies Ltd., signaling confidence in the company's future.
• The purchase of 5,784 ordinary shares at an average price of $35.8305 indicates a belief in the company's value.
• The transaction was executed under a Rule 10b5-1(c) plan, suggesting a pre-planned investment strategy rather than an opportunistic one.

Future Outlook

This Form 4 filing does not contain any forward-looking statements or guidance.

Industry Context

This filing reports an insider transaction and does not provide broader industry context or trends. It reflects an investment decision by a significant shareholder and director within Sol-Gel Technologies Ltd.

Related Party Transactions

• The reported transaction is a related party transaction, as Opaleye Management Inc. is a 10% owner and director of Sol-Gel Technologies Ltd.

Stakeholder Impact

• Shareholders: The increase in ownership by a significant insider may instill greater confidence among existing and potential shareholders, potentially leading to positive sentiment.
• Employees, Customers, Suppliers, Creditors: This specific filing is unlikely to have a direct or immediate impact on these stakeholders, as it primarily concerns ownership structure.

Key Dates

Recommendation

The purchase of additional shares by a 10% owner and director, especially under a Rule 10b5-1 plan, typically signals strong insider confidence in the company's current valuation and future prospects. This often serves as a positive indicator for investors, suggesting the stock may be undervalued or poised for growth.

Keywords

Sol-Gel Technologies Ltd., SLGL, Opaleye Management Inc., Insider Trading, Form 4, Beneficial Ownership, Share Purchase, 10% Owner, Director, Equity Acquisition