SCHEDULE: American Century Group Amends Si-Bone Stake to 6.6%

American Century Investment Management, along with its affiliates, has updated its beneficial ownership in Si-Bone, Inc. to 6.6% of common stock as of September 30, 2025.

Summary

• American Century Investment Management, Inc., American Century Companies, Inc., and Stowers Institute for Medical Research collectively beneficially own 2,838,107 shares of Si-Bone, Inc. common stock, representing 6.6% of the class.
• American Century Mutual Funds, Inc. beneficially owns 2,272,347 shares, representing 5.3% of the class.
• The filing is an Amendment No. 2 to Schedule 13G, indicating an update to previously reported beneficial ownership.
• The reporting persons certify that the securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of Si-Bone, Inc.

Sentiment

Score: 6

Explanation: The sentiment is moderately positive due to the disclosure of significant institutional ownership by a reputable investment group, which can be interpreted as a vote of confidence. The filing itself is a routine disclosure, so it's not overwhelmingly positive or negative, but the underlying fact of substantial ownership is generally viewed favorably.

Positives

• Significant institutional ownership by American Century group, including Stowers Institute for Medical Research, may signal confidence in Si-Bone, Inc.'s long-term prospects.
• The beneficial ownership is stated to be for ordinary course of business, not for control, which suggests a passive investment strategy.

Negatives

• NA

Risks

• The filing addresses the potential regulatory risk that the securities could be perceived as being held for the purpose of changing or influencing control, which the reporting persons explicitly disclaim.

Future Outlook

NA

Industry Context

This filing reflects a significant institutional investment in Si-Bone, Inc., a company operating in the medical device or healthcare sector. Large institutional holdings are common in established and growing companies within this industry, indicating investor interest in the company's market position and potential for innovation.

Comparison to Industry Standards

• NA

Stakeholder Impact

• Shareholders: The disclosure of significant institutional ownership by American Century and Stowers Institute may provide a level of confidence and stability, potentially influencing investor perception positively.
• Company Management: Awareness of a large institutional holder can influence strategic decisions, though the filing states the ownership is not for control purposes.

Key Dates

Keywords

Si-Bone, American Century, Stowers Institute, Beneficial Ownership, Schedule 13G, Common Stock, Institutional Investor, Medical Research, Investment Management