SCHEDULE: Redmile Group Adjusts Shattuck Labs Stake

Redmile Group, LLC and associated entities have updated their Schedule 13D filing, reporting a beneficial ownership of 9.9% in Shattuck Labs, Inc. as of July 17, 2026.

Summary

• Redmile Group, LLC, along with Jeremy C. Green and Redmile Biopharma Investments II, L.P. (collectively, the "Reporting Persons"), have filed an amendment to their Schedule 13D concerning Shattuck Labs, Inc.
• As of July 17, 2026, the Reporting Persons collectively beneficially own 10,019,421 shares of Shattuck Labs' common stock, representing 9.9% of the class.
• This ownership includes shares held directly and shares issuable upon exercise of pre-funded warrants, subject to a 9.99% beneficial ownership limitation.
• On July 17, 2026, certain Redmile Funds acquired an additional 143,808 shares for approximately $1,000,000 at an average price of $7.46 per share.
• The filing details various transactions, including sales and purchases, between July 10, 2026, and July 17, 2026.

Sentiment

Score: 5

Explanation: StockSavvy.ai views this filing as neutral, primarily reflecting routine adjustments in beneficial ownership and trading activity by a significant investor, without clear indicators of significant positive or negative developments for the company itself.

Positives

• Redmile Group has increased its investment in Shattuck Labs, Inc., indicating continued confidence in the company's prospects.
• The acquisition of 143,808 shares on July 17, 2026, at $7.46 per share, demonstrates active participation in the market.
• The beneficial ownership remains below the 9.99% threshold, allowing for potential future acquisitions without triggering immediate reporting obligations.

Negatives

• The filing details significant sales activity by Redmile Group between July 10 and July 16, 2026, prior to the reported purchase.
• The total beneficial ownership is calculated based on shares held and shares issuable from warrants, which introduces a layer of potential dilution or uncertainty.

Risks

• The beneficial ownership limitation of 9.99% on the exercise of pre-funded warrants could restrict the ability to fully exercise these warrants.
• The active trading by Redmile Group, including substantial sales, could indicate a dynamic investment strategy or potential concerns about short-term price movements.

Future Outlook

The filing does not contain specific forward-looking statements or guidance from Shattuck Labs, Inc. It primarily details the current beneficial ownership and recent transactions by Redmile Group.

Industry Context

StockSavvy.ai notes that Schedule 13D filings are critical for tracking significant institutional investor activity. Redmile Group's active management of its stake in Shattuck Labs, Inc., including both purchases and sales, is typical of activist or strategic investment funds seeking to influence or capitalize on perceived value in the biotechnology sector.

Stakeholder Impact

• Shareholders: The active trading by a significant investor like Redmile Group can influence market sentiment and stock price volatility.
• Management: Increased scrutiny from substantial shareholders may prompt management to focus on performance and strategic execution.

Next Steps

• Continued monitoring of Redmile Group's trading activity and beneficial ownership in Shattuck Labs, Inc.
• Observation of Shattuck Labs, Inc.'s operational and financial performance to understand the context of Redmile's investment strategy.

Key Dates

Recommendation

The filing indicates an active but balanced approach by a significant investor, with both purchases and sales reported. The overall beneficial ownership percentage remains substantial but within reporting thresholds. Without further information on Shattuck Labs' specific business performance or Redmile's strategic intentions, a 'hold' recommendation is prudent, suggesting investors monitor further developments.

Keywords

Schedule 13D, Shattuck Labs, Redmile Group, Beneficial Ownership, Securities Filing, Investment Funds, Pre-funded Warrants, SEC Filing