SCHEDULE: FMR LLC & Abigail Johnson Report 2.5% Stake in REZOLUTE INC

FMR LLC and Abigail P. Johnson have reported a 2.5% beneficial ownership stake in REZOLUTE INC's common stock as of December 31, 2025.

Summary

• FMR LLC and Abigail P. Johnson jointly reported beneficial ownership of 2,305,568 shares of REZOLUTE INC's common stock.
• This represents 2.5% of the total outstanding common stock of REZOLUTE INC.
• The shares were acquired and are held in the ordinary course of business, not for the purpose of changing or influencing control of the issuer.
• FMR LLC holds sole voting power over 2,305,168 shares, while both FMR LLC and Abigail P. Johnson hold sole dispositive power over 2,305,568 shares.
• Abigail P. Johnson is a Director, Chairman, and CEO of FMR LLC, and the Johnson family, including Abigail P. Johnson, are predominant owners of FMR LLC, forming a controlling group.

Sentiment

Score: 6

Explanation: The filing indicates a continued passive institutional investment by a reputable firm, which is generally a neutral to slightly positive signal for the company's stability and market perception, but it doesn't provide new operational or financial performance data.

Positives

• A significant institutional investor, FMR LLC, maintains a stake in REZOLUTE INC, indicating continued interest.
• The ownership is reported as being in the ordinary course of business, suggesting a long-term investment perspective rather than an activist stance.

Negatives

• The reported ownership percentage of 2.5% is a passive stake, below the 5% threshold that would typically signal a more significant, potentially influential, investment.

Risks

• No specific risks related to REZOLUTE INC's operations or financial health are mentioned in this Schedule 13G filing, as it focuses solely on beneficial ownership.

Future Outlook

This filing is a beneficial ownership report and does not contain forward-looking statements or guidance regarding REZOLUTE INC's future performance or FMR LLC's investment strategy beyond the stated passive holding.

Management Comments

• The securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities.

Industry Context

This Schedule 13G filing reflects a passive investment by a major asset manager, FMR LLC, in REZOLUTE INC. Such filings are routine for institutional investors holding less than 5% of a company's stock without intent to influence control. It provides transparency on significant, albeit non-controlling, institutional holdings, which can be a positive signal for market confidence in the issuer.

Comparison to Industry Standards

• The 2.5% stake is a standard passive institutional investment, typical for large asset managers like FMR LLC who diversify holdings across many companies.
• This level of ownership is below the 5% threshold that would typically trigger more scrutiny or suggest an activist position, aligning with the 'ordinary course of business' certification.
• Compared to other institutional investors, a 2.5% stake is a moderate position, indicating interest but not necessarily a high-conviction bet that would be seen with larger, more concentrated holdings.

Stakeholder Impact

• Shareholders: Provides transparency on a significant institutional holding, potentially reinforcing market confidence.
• Management: Awareness of a notable institutional investor's passive stake.

Next Steps

• FMR LLC and Abigail P. Johnson will continue to monitor their investment in REZOLUTE INC.
• Further Schedule 13G amendments would be filed if there are material changes to their beneficial ownership (e.g., crossing a 1% threshold up or down, or exceeding 10%).

Key Dates

Recommendation

This Schedule 13G filing is a routine disclosure of a passive institutional stake by FMR LLC and Abigail P. Johnson in REZOLUTE INC, maintaining a 2.5% ownership. It indicates continued interest from a major asset manager but does not provide new information regarding REZOLUTE INC's operational performance, financial health, or strategic direction. As such, it offers no new fundamental data to warrant a change in investment thesis, suggesting a 'hold' recommendation for existing investors.

Keywords

REZOLUTE INC, FMR LLC, Abigail P. Johnson, Common Stock, Beneficial Ownership, Schedule 13G, Institutional Investor, Equity Stake