SCHEDULE: Kirk-Controlled Entities Divest Precigen Shares

Entities controlled by Randal J. Kirk sold nearly 3 million shares of Precigen, Inc. common stock for approximately $12.3 million in open market transactions.

Summary

• This is Amendment No. 21 to the Schedule 13D for Precigen, Inc. (formerly Intrexon Corporation).
• The reporting persons are Randal J. Kirk, the R.J. Kirk Declaration of Trust, and Third Security, LLC.
• Kapital Joe, LLC, an entity under the common control of Mr. Kirk, sold an aggregate of 2,966,293 shares of Common Stock in open market transactions.
• These sales by Kapital Joe, LLC occurred between November 19, 2025, and November 21, 2025, inclusive, yielding aggregate net proceeds of approximately $12,290,420.
• Separately, on September 30, 2025, Sunset 2020, LLC, another entity controlled by Mr. Kirk, sold 1,809,667 shares of Common Stock in open market transactions at a weighted average price of $3.41, for cumulative gross proceeds of approximately $6,168,742.
• The percentage ownership for the reporting persons is calculated based on 353,824,449 shares of Common Stock issued and outstanding as of October 31, 2025, adjusted for exercisable options and warrants.
• Randal J. Kirk beneficially owns 141,519,399 shares (38.1%), including 906,512 exercisable options and 16,666,667 exercisable warrants.
• The R.J. Kirk Declaration of Trust beneficially owns 98,831,434 shares (26.6%), including 16,666,667 exercisable warrants.
• Third Security, LLC beneficially owns 24,487,991 shares (6.6%).

Sentiment

Score: 4

Explanation: The filing discloses significant share sales by entities controlled by a major shareholder, Randal J. Kirk. While a factual disclosure, large insider sales can sometimes be interpreted by the market as a lack of confidence or a move to diversify, potentially exerting downward pressure on sentiment.

Negatives

• The sale of a significant number of shares by entities controlled by a major shareholder, Randal J. Kirk, could be perceived by the market as a negative signal regarding future prospects or a move to diversify holdings.

Future Outlook

No forward-looking statements or guidance are provided in this filing.

Industry Context

This filing primarily concerns changes in beneficial ownership by a major shareholder and does not provide specific information to analyze broader industry trends or competitive positioning.

Related Party Transactions

• Kapital Joe, LLC, an entity under the common control of Randal J. Kirk, sold 2,966,293 shares of Common Stock.
• Sunset 2020, LLC, an entity controlled by Randal J. Kirk, sold 1,809,667 shares of Common Stock.

Stakeholder Impact

• Shareholders: The sale of a substantial number of shares by a controlling shareholder may lead to concerns about insider confidence and could potentially increase selling pressure on the stock.

Key Dates

Recommendation

The filing details significant share sales by entities controlled by a major shareholder, Randal J. Kirk. While insider selling can be a bearish signal, this Schedule 13D amendment primarily serves as a disclosure of ownership changes rather than a comprehensive financial or operational update. Without additional context from the company's financial performance or strategic direction, a 'hold' recommendation is prudent to observe market reaction and wait for further fundamental information before making a definitive investment decision.

Keywords

Precigen Inc, PRGN, Randal J. Kirk, Schedule 13D, share sale, insider selling, beneficial ownership, Third Security LLC, Kapital Joe LLC, common stock