SCHEDULE: Vanguard Group Amends Omeros Corp Stake

The Vanguard Group has filed an amendment to its Schedule 13G, reporting a 4.91% beneficial ownership stake in Omeros Corp as of September 30, 2025.

Summary

• The Vanguard Group, an investment adviser, reported beneficial ownership of 3,346,958 shares of Omeros Corp common stock.
• This represents 4.91% of Omeros Corp's outstanding common stock.
• The filing is an Amendment No. 1 to a previously filed Schedule 13G.
• Vanguard holds sole dispositive power over 2,887,220 shares and shared dispositive power over 459,738 shares.
• Vanguard holds shared voting power over 438,694 shares and no sole voting power.
• The securities were acquired and are held in the ordinary course of business, not for the purpose of changing or influencing control of Omeros Corp.

Sentiment

Score: 5

Explanation: The filing is a routine disclosure of an institutional investor's passive stake, providing no new operational or financial information about Omeros Corp. The percentage is just under 5%, indicating a non-controlling, passive investment.

Positives

• A major institutional investor like The Vanguard Group maintains a significant stake in Omeros Corp, indicating continued confidence in the company's long-term prospects from a passive investment perspective.
• The holding is part of Vanguard's ordinary course of business, suggesting a stable, non-activist investment.

Negatives

• The reported beneficial ownership of 4.91% is below the 5% threshold, which could indicate a slight reduction in stake from a previous filing, or simply a routine update where the position is now below 5%.

Risks

• No specific risks related to Omeros Corp's operations or financial health are disclosed in this filing, as it pertains solely to beneficial ownership by an institutional investor.

Future Outlook

NA

Management Comments

• By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under 240.14a-11.

Industry Context

NA

Stakeholder Impact

• Shareholders: Provides transparency regarding a significant institutional holder's stake, confirming a passive investment approach by Vanguard.

Key Dates

Keywords

Omeros Corp, Vanguard Group, Schedule 13G, Beneficial Ownership, Common Stock, Institutional Investor, Equity Stake, SEC Filing