SCHEDULE: George Family Increases Mesoblast Stake to 21.59%

Gregory George and related entities have significantly increased their beneficial ownership in Mesoblast Limited, now holding 21.59% of the company's ordinary shares.

Summary

• Gregory George, along with his sons James George and Grant George, and G to the Fourth Investments, LLC, have reported an aggregate beneficial ownership of Mesoblast Limited.
• Gregory George is the largest beneficial owner, holding 275,851,734 ordinary shares, which represents 21.59% of the company's outstanding shares.
• His beneficial ownership includes 137,123,887 shares over which he has sole voting and dispositive power, and 138,727,847 shares over which he has shared voting and dispositive power.
• The shares under Gregory George's shared control include 123,060,227 shares held by G to the Fourth Investments, LLC, and 6,000,000 shares each held by his sons, James George and Grant George.
• G to the Fourth Investments, LLC beneficially owns 126,727,847 ordinary shares, representing 9.92% of the class.
• James George and Grant George each beneficially own 6,000,000 ordinary shares, each representing 0.47% of the class.
• The beneficial ownership is based on 1,277,782,187 ordinary shares of Mesoblast Limited outstanding as of September 12, 2025.

Sentiment

Score: 5

Explanation: This is a factual disclosure of beneficial ownership and does not inherently convey positive or negative sentiment regarding the company's performance or prospects. It simply reports a change in a significant shareholder's stake.

Future Outlook

NA

Industry Context

This filing indicates a significant concentration of ownership by a single individual and related entities in Mesoblast Limited, a biotechnology company. Such substantial stakes can signal long-term commitment or potential influence over corporate strategy, which is a notable factor for investors in the often capital-intensive and volatile biotech sector.

Related Party Transactions

• Gregory George is deemed to be the beneficial owner of shares held by his sons, James George and Grant George, and shares held by G to the Fourth Investments, LLC, where he is a manager, indicating related party ownership and control.

Stakeholder Impact

• Shareholders: The significant stake held by Gregory George and related entities could influence corporate governance and strategic decisions, potentially impacting other shareholders' interests.
• Management: A large, concentrated ownership group may exert greater influence on management decisions and company direction.

Key Dates

Keywords

Mesoblast Limited, Beneficial Ownership, Schedule 13G, Gregory George, Institutional Investor, Shareholder Stake, Ordinary Shares, American Depositary Receipts, Biotechnology