SCHEDULE: FMR LLC, Abigail Johnson Disclose 15% Stake in LENZ THERAPEUTICS

Sentiment:

Beneficial Ownership Report 7 November 2025 11:13 AM

FMR LLC and Abigail P. Johnson have reported a beneficial ownership of 15.0% in LENZ THERAPEUTICS INC's common stock as of October 31, 2025.

Summary

FMR LLC and Abigail P. Johnson have filed a Schedule 13G, disclosing beneficial ownership of 4,278,243.81 shares of LENZ THERAPEUTICS INC common stock.
This aggregate amount represents 15.0% of the total outstanding common stock of LENZ THERAPEUTICS INC.
FMR LLC holds sole voting power over 4,277,858.12 shares and sole dispositive power over 4,278,243.81 shares.
Abigail P. Johnson, as an individual, holds sole dispositive power over 4,278,243.81 shares, with no sole or shared voting power directly attributed.
Fidelity Growth Company Commingled Pool is known to have an interest of 1,621,042.00 shares, representing 5.7% of the total outstanding common stock as of October 31, 2025.
FMR LLC is classified as a parent holding company, and Abigail P. Johnson is classified as an individual.
Several FMR LLC subsidiaries and affiliates, including Fidelity Management & Research Company LLC and Fidelity Management Trust Company, beneficially own 5% or greater of the security class.

Sentiment

Score: 7

Explanation: The disclosure of a significant 15.0% stake by FMR LLC and Abigail P. Johnson in LENZ THERAPEUTICS INC is generally viewed favorably by the market, as it signals strong institutional confidence in the company's prospects.

Positives

Significant institutional investment from FMR LLC, a major asset manager, indicates confidence in LENZ THERAPEUTICS INC.
The 15.0% stake suggests a substantial long-term interest from a prominent financial institution.

Future Outlook

Industry Context

Stakeholder Impact

Shareholders: The significant stake by FMR LLC and Abigail P. Johnson could be seen as a vote of confidence, potentially attracting other investors and positively influencing share price. It also indicates a major institutional presence on the shareholder register.

Key Dates

Date	Description
2023-01-03	Effective date of Power of Attorney for Stephanie J. Brown on behalf of FMR LLC.
2023-01-10	Date of Schedule 13G filing by FMR LLC where Power of Attorney (accession number -23-000003) was incorporated by reference.
2023-01-26	Effective date of Power of Attorney for Stephanie J. Brown on behalf of Abigail P. Johnson.
2023-01-31	Date of Schedule 13G filing by FMR LLC where Power of Attorney (accession number -23-000038) for Abigail P. Johnson was incorporated by reference.
2025-10-31	Date of event which requires filing of this statement (beneficial ownership snapshot date).
2025-11-06	Date of joint filing agreement and signatures for the Schedule 13G.

Recommendation

hold

The filing indicates a substantial 15.0% beneficial ownership by FMR LLC and Abigail P. Johnson in LENZ THERAPEUTICS INC. While this significant institutional stake is generally a positive signal, demonstrating confidence from a major asset manager, a Schedule 13G filing primarily reports ownership and does not provide operational or financial performance data. Therefore, without additional fundamental analysis of LENZ THERAPEUTICS INC's business, financials, and market position, a "hold" recommendation is prudent, acknowledging the positive signal of institutional interest while awaiting more comprehensive information for a stronger stance.

Keywords

LENZ THERAPEUTICS INC, FMR LLC, Abigail P. Johnson, Beneficial Ownership, Schedule 13G, Common Stock, Institutional Investment, Fidelity Growth Company Commingled Pool, Equity Stake

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