SCHEDULE: FMR LLC Discloses 12.2% Stake in Disc Medicine

FMR LLC and Abigail P. Johnson have reported a beneficial ownership of 12.2% in Disc Medicine Inc.'s common stock as of July 31, 2025.

Summary

• FMR LLC and Abigail P. Johnson jointly reported beneficial ownership of 4,221,058.48 shares of Disc Medicine Inc. common stock.
• This represents 12.2% of the total outstanding common stock of Disc Medicine Inc.
• FMR LLC holds sole voting power over 4,220,689.00 shares and sole dispositive power over 4,221,058.48 shares.
• Abigail P. Johnson holds sole dispositive power over 4,221,058.48 shares.
• The filing is an Amendment No. 2 to a Schedule 13G, indicating an update to a previously reported ownership stake.
• FMR LLC is classified as a parent holding company, and Abigail P. Johnson is an individual.
• Several FMR LLC subsidiaries, including Fidelity Management & Research Company LLC, are identified as entities beneficially owning shares, with Fidelity Management & Research Company LLC beneficially owning 5% or greater of the outstanding shares.

Sentiment

Score: 5

Explanation: The filing is a factual disclosure of beneficial ownership by a major institutional investor and does not contain information that would inherently indicate a positive or negative sentiment regarding the issuer's performance or outlook.

Positives

• A significant beneficial ownership stake by FMR LLC, a major institutional investor, may signal confidence in Disc Medicine Inc.

Negatives

• NA

Risks

• NA

Future Outlook

NA

Industry Context

This filing is a disclosure of a significant ownership stake by a major investment firm in Disc Medicine Inc. It does not provide information on broader industry trends or the competitive landscape.

Related Party Transactions

• The filing details the internal control structure of FMR LLC, noting that members of the Johnson family, including Abigail P. Johnson, are the predominant owners of FMR LLC's Series B voting common shares (49% voting power) and may be deemed a controlling group. This clarifies the relationship among the reporting persons and their control over FMR LLC.

Stakeholder Impact

• Shareholders: The disclosure of a significant institutional stake by FMR LLC may influence investor perception and potentially stock liquidity.

Key Dates

Keywords

DISC MEDICINE INC, FMR LLC, Abigail P. Johnson, Schedule 13G, Beneficial Ownership, Common Stock, Institutional Investor, Ownership Disclosure, SEC Filing