Form 4: Opaleye Management Inc. Increases Stake in Codexis, Inc.

Opaleye Management Inc. reports purchasing 100,000 shares of Codexis, Inc. at an average price of $2.6135, increasing its total holdings to 9,065,000 shares.

Summary

• Opaleye Management Inc., a 10% owner of Codexis, Inc., filed a Form 4 with the SEC.
• On March 6, 2025, Opaleye Management Inc. purchased 100,000 shares of Codexis common stock at a weighted average price of $2.6135 per share.
• The purchases were made in multiple transactions with prices ranging from $2.4784 to $2.71 inclusive.
• Following the transaction, Opaleye Management Inc. beneficially owns 9,065,000 shares of Codexis common stock through Opaleye, L.P.
• Opaleye Management Inc. disclaims beneficial ownership of the shares except to the extent of its pecuniary interest.

Sentiment

Score: 6

Explanation: Neutral sentiment. This is a routine disclosure of a stock purchase by a major shareholder. The increased stake could be seen as a positive, but the filing itself is simply a required disclosure.

Positives

• Opaleye Management Inc.'s increased investment in Codexis could be interpreted as a positive signal about the company's prospects.

Management Comments

• Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein.

Industry Context

This filing reflects the investment activity of a significant shareholder in Codexis, a company in the biotechnology sector. Such filings are common and provide transparency into the ownership structure and investment decisions of major stakeholders.

Stakeholder Impact

• The increased stake by Opaleye Management Inc. could positively influence shareholder confidence.

Key Dates