SCHEDULE: State Street Reports 4.8% Stake in CareDx

State Street Corporation has disclosed beneficial ownership of 4.8% of CareDx Inc.'s common stock as of June 30, 2026.

Summary

• State Street Corporation has filed a Schedule 13G, indicating its beneficial ownership of 2,468,858 shares of CareDx Inc. common stock.
• This represents 4.8% of the total class of securities.
• The filing date is August 7, 2026, with the event date requiring the filing being June 30, 2026.
• State Street Corporation acts as an investment adviser (IA) through various subsidiaries, including SSGA FUNDS MANAGEMENT, INC.

Sentiment

Score: 3

Explanation: StockSavvy.ai views this as a neutral filing, primarily reporting a change in beneficial ownership percentage without significant new strategic or financial information.

Positives

• State Street Corporation's investment indicates confidence or a strategic holding in CareDx Inc.
• The filing is a standard disclosure, ensuring transparency in ownership.

Negatives

• The filing does not provide any new financial performance data or strategic updates for CareDx Inc.
• The ownership percentage is below the threshold that typically triggers active influence or control.

Risks

• Potential for future changes in State Street's ownership stake, which could impact market dynamics.
• The filing itself does not introduce new risks to CareDx Inc., but reflects existing market conditions and investor positions.

Future Outlook

This filing is a historical disclosure of ownership as of June 30, 2026, and does not contain forward-looking statements or guidance from CareDx Inc.

Management Comments

• "By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under 240.14a-11."
• "After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct."

Industry Context

StockSavvy.ai notes that institutional ownership filings like this are common in the healthcare and diagnostics sector, reflecting the active participation of large financial institutions in publicly traded companies.

Comparison to Industry Standards

• Ownership stakes of 4.8% by large financial institutions like State Street are typical for publicly traded companies in the healthcare sector.
• This level of ownership is generally considered passive, meaning it does not typically confer control or significant influence over the company's strategic decisions, unlike activist investor stakes which often exceed 5% and are accompanied by direct engagement.

Stakeholder Impact

• Shareholders: The filing provides transparency on a significant institutional holder, which can be viewed positively by the market.
• Management: The filing confirms a passive ownership stake, suggesting no immediate pressure for control changes from this holder.

Next Steps

• State Street Corporation will continue to hold its shares in CareDx Inc. as per its investment strategy.
• Future filings will be made by State Street Corporation if its beneficial ownership percentage changes significantly.

Key Dates

Keywords

CareDx, State Street Corporation, Schedule 13G, Beneficial Ownership, Institutional Investor, Healthcare, Diagnostics