SCHEDULE: Sio Capital Management Updates Aprea Therapeutics Stake
Beneficial Ownership Update
Sio Capital Management, LLC has updated its beneficial ownership in Aprea Therapeutics, Inc., reporting a 1.93% stake as of September 30, 2025.
Summary
- Sio Capital Management, LLC, an investment adviser, beneficially owns 112,223 shares of Aprea Therapeutics, Inc. common stock.
- This ownership represents 1.93% of Aprea Therapeutics' outstanding common stock.
- The calculation is based on 5,825,261 shares of common stock outstanding as of August 11, 2025, as reported in the Issuer's Form 10-K filed on August 12, 2025.
- Sio Capital Management, LLC holds shared voting power and shared dispositive power over all 112,223 shares.
- The securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing the control of Aprea Therapeutics, Inc.
Sentiment
Score: 5
Explanation: The filing is a routine, factual disclosure of beneficial ownership and does not contain information that would significantly alter the sentiment towards the company or the reporting entity.
Positives
- An institutional investor, Sio Capital Management, LLC, maintains a stake in Aprea Therapeutics, Inc., indicating continued interest.
Future Outlook
This filing is a routine disclosure of beneficial ownership and does not contain any forward-looking statements or guidance regarding the issuer's future performance or strategy.
Industry Context
This filing represents a standard disclosure by an institutional investment adviser, Sio Capital Management, LLC, regarding its passive ownership stake in Aprea Therapeutics, Inc. Such disclosures are common in the financial industry and provide transparency on significant holdings by investment funds.
Stakeholder Impact
- Shareholders: Provides transparency regarding an institutional investor's stake, confirming Sio Capital Management, LLC's continued, passive investment in the company.
Key Dates
| Date | Description |
|---|---|
| 08/11/2025 | Date as of which 5,825,261 shares of common stock were outstanding, as reported by Aprea Therapeutics, Inc. |
| 08/12/2025 | Date Aprea Therapeutics, Inc. filed its Form 10-K with the SEC. |
| 09/30/2025 | Date of the event which required the filing of this Schedule 13G amendment. |
| 10/31/2025 | Date the Schedule 13G Amendment No. 4 was signed by Sio Capital Management, LLC. |
Keywords
Aprea Therapeutics, Sio Capital Management, Beneficial Ownership, Schedule 13G, Common Stock, Institutional Investment
Disclaimer:The information provided here is for general informational purposes only and does not constitute financial advice, recommendation, or endorsement of any kind. It may contain errors or omissions. You should not rely on this information to make financial decisions. Always seek the advice of a qualified financial professional before making any investment or financial decisions. Use of this information is at your own risk.