SCHEDULE 13G/A: Janus Henderson Group PLC Discloses Minimal Stake in Applied Therapeutics Inc.

Janus Henderson Group PLC has filed an amended Schedule 13G, reporting a 0.0% beneficial ownership stake in Applied Therapeutics Inc. as of December 31, 2024.

Summary

• Janus Henderson Group PLC, a Jersey-based investment adviser and holding company, filed an Amendment No. 3 to Schedule 13G regarding its beneficial ownership in Applied Therapeutics Inc.
• As of December 31, 2024, Janus Henderson Group PLC beneficially owned 35,791 shares of Applied Therapeutics Inc. Common Stock.
• This ownership represents 0.0% of the total class of securities.
• The reporting person holds shared voting power and shared dispositive power over all 35,791 shares.
• The filing certifies that the securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of the issuer.

Sentiment

Score: 5

Explanation: The document is a routine regulatory filing disclosing beneficial ownership and contains no information that would significantly alter sentiment, positive or negative. The ownership percentage is negligible.

Positives

• The filing indicates that Janus Henderson Group PLC's stake was acquired and is held in the ordinary course of business, not for control purposes, suggesting a passive investment intent.

Negatives

• The reported beneficial ownership of 0.0% is a negligible stake, indicating no significant investment or strategic interest from Janus Henderson Group PLC.

Risks

• No specific risks related to Applied Therapeutics Inc. or its operations are disclosed in this Schedule 13G filing.

Future Outlook

This Schedule 13G filing does not contain any forward-looking statements or guidance regarding Applied Therapeutics Inc.'s future operations or financial performance.

Industry Context

This filing is a routine disclosure of beneficial ownership by an investment firm and does not provide insights into broader industry trends or competitive dynamics within the pharmaceutical or biotechnology sector where Applied Therapeutics Inc. operates.

Stakeholder Impact

• The filing indicates a negligible ownership stake by Janus Henderson Group PLC, suggesting minimal direct impact on shareholders, employees, customers, suppliers, or creditors of Applied Therapeutics Inc. as it does not imply any strategic shift or significant investment.

Key Dates

Keywords

Applied Therapeutics Inc., Janus Henderson Group PLC, Schedule 13G, Beneficial Ownership, Common Stock, SEC Filing, Investment Adviser, Holding Company, Passive Investment