Form 4: Annovis Bio Director Boosts Stake with $70K Stock Purchase

Annovis Bio, Inc. Director and 10% owner Michael B. Hoffman acquired 20,000 shares of common stock for approximately $70,000 through open market purchases.

Summary

• Michael B. Hoffman, a Director and 10% owner of Annovis Bio, Inc. (ANVS), reported the acquisition of 20,000 shares of common stock.
• The shares were purchased on November 21, 2025, through two separate transactions.
• The first transaction involved 10,000 shares at a price of $3.49 per share.
• The second transaction involved 10,000 shares at a price of $3.50 per share.
• These transactions were made pursuant to a Rule 10b5-1(c) plan.
• Following these purchases, Hoffman directly beneficially owns 2,490,539 shares of common stock.
• Additionally, Hoffman indirectly beneficially owns 223,357 shares through The 2018 Jane and Michael Hoffman Descendants Trust, over which he has voting and investment power.

Sentiment

Score: 7

Explanation: The acquisition of shares by a Director and 10% owner, even if pre-planned, generally indicates management confidence in the company's valuation and future performance.

Positives

• Director and 10% owner Michael B. Hoffman acquired 20,000 shares of common stock, signaling confidence in the company's future prospects.
• The purchases were made at prices of $3.49 and $3.50 per share, totaling approximately $69,900.
• The transactions were executed under a Rule 10b5-1(c) plan, indicating a pre-planned investment strategy by a key insider.

Future Outlook

This filing does not contain forward-looking statements or guidance regarding the company's future outlook.

Industry Context

Insider buying, particularly by a director and significant shareholder, is often interpreted by the market as a positive signal, suggesting that those closest to the company believe its stock is undervalued or has strong future prospects, potentially outperforming competitors.

Related Party Transactions

• Michael B. Hoffman indirectly beneficially owns 223,357 shares through The 2018 Jane and Michael Hoffman Descendants Trust, a family trust over which he has voting and investment power.

Stakeholder Impact

• Shareholders may view this insider buying as a positive indicator of management's belief in the company's value and future growth, potentially boosting investor confidence.

Key Dates

Recommendation

The decision by a Director and 10% owner to increase their stake, even through a pre-planned Rule 10b5-1 program, signals strong insider confidence in Annovis Bio's future prospects and current valuation. This action suggests that a key insider believes the stock is undervalued or poised for growth, making it a positive indicator for potential investors.

Keywords

Annovis Bio, ANVS, Michael B. Hoffman, insider trading, Form 4, stock purchase, director, 10% owner, beneficial ownership, Rule 10b5-1