SCHEDULE: Logos Global Reports Zero Annexon Stock Ownership

Sentiment:

Beneficial Ownership Update 14 August 2025 1:14 PM

Logos Global Management LP and its affiliates have filed an amended Schedule 13G, reporting zero beneficial ownership in Annexon, Inc. common stock.

Worse than expectedThe filing indicates that Logos Global Management LP and its affiliates, previously a significant beneficial owner, now hold 0% of Annexon, Inc. common stock. While the reasons for this divestment are not disclosed, the complete exit of a major institutional investor can be perceived as a negative signal by the market.

Summary

Logos Global Management LP, Logos Global Management GP LLC, Logos Global Master Fund LP, Logos GP LLC, and Arsani William have filed an Amendment No. 1 to Schedule 13G.
The filing indicates that as of June 30, 2025, all reporting persons beneficially own 0.00 shares of Annexon, Inc. Common Stock.
This represents 0% of the class of Annexon, Inc. Common Stock.
The reporting persons disclaim beneficial ownership of Common Stock except to the extent of their pecuniary interest therein.
The securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of Annexon, Inc.

Sentiment

Score: 4

Explanation: The sentiment is slightly negative as a significant institutional investor has reduced its stake to zero, which could be interpreted as a lack of confidence or a strategic exit, although no reasons are provided in the filing.

Negatives

A significant investor, Logos Global Management LP and its affiliates, has reduced their beneficial ownership in Annexon, Inc. to 0%, indicating a complete divestment or reduction below the reporting threshold.

Future Outlook

No forward-looking statements or guidance regarding Annexon, Inc.'s operations or financial performance are provided in this beneficial ownership filing.

Industry Context

This filing reflects a change in an institutional investor's position in a biotechnology company. Such divestments by investment funds are part of routine portfolio management and can occur for various reasons, including rebalancing, strategic shifts, or changes in investment thesis, and do not inherently reflect on the operational performance of the issuer.

Stakeholder Impact

Shareholders of Annexon, Inc. may note the complete divestment of shares by Logos Global Management LP and its affiliates, which could influence market perception and trading activity.

Key Dates

Date	Description
06/30/2025	Date of event which required the filing of this statement (change in beneficial ownership).
08/13/2025	Date the Schedule 13G Amendment No. 1 was signed and filed.

Keywords

Annexon, ANXN, Logos Global Management, Schedule 13G, Beneficial Ownership, Divestment, Institutional Investor

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