ANNX.NASDAQAnnexon, INC

SCHEDULE 13G/A: BlackRock Boosts Annexon Stake to 6.1%

Sentiment:

Beneficial Ownership Report


BlackRock, Inc. has reported an increased beneficial ownership of 6.1% in Annexon Inc.'s common stock as of December 31, 2025.

Summary

  • BlackRock, Inc. beneficially owns 8,868,755 shares of Annexon Inc. common stock.
  • This ownership represents 6.1% of Annexon Inc.'s outstanding common stock.
  • BlackRock holds sole voting power over 8,773,698 shares and sole dispositive power over 8,868,755 shares.
  • The securities were acquired and are held in the ordinary course of business, not for the purpose of changing or influencing the control of Annexon Inc.
  • Several BlackRock subsidiaries, including BlackRock Advisors, LLC and BlackRock Investment Management, LLC, are involved in the beneficial ownership, with at least one entity owning 5% or greater of the outstanding shares.

Sentiment

Score: 6

Explanation: The filing is largely factual, reporting a passive ownership stake. The increase in institutional ownership by a major firm like BlackRock is generally viewed as a neutral to slightly positive signal, indicating continued investor interest, but it does not provide operational or financial performance insights.

Positives

  • Increased institutional ownership by a major asset manager like BlackRock can signal confidence in Annexon Inc.'s long-term prospects.
  • The holding is stated to be in the ordinary course of business, indicating a passive investment rather than an activist stance.

Future Outlook

This filing does not contain any forward-looking statements or guidance regarding Annexon Inc.'s business or financial performance.

Management Comments

  • BlackRock, Inc. certifies that the securities were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities.

Industry Context

This filing reflects a routine disclosure of significant passive institutional ownership, common in the biotechnology and pharmaceutical sectors where large asset managers like BlackRock frequently hold stakes in publicly traded companies. Such filings provide transparency into major shareholders but do not typically indicate strategic shifts for the underlying company.

Corporate Governance

Change TypeDescriptionEffective DateImpact Assessment
Internal Policy Update (Reporting Entity)BlackRock, Inc. executed a new Power of Attorney, effective January 21, 2025, which revokes a previous Power of Attorney dated April 30, 2023. This new document designates several individuals as attorneys-in-fact for executing and filing various SEC and other regulatory documents on behalf of BlackRock and its subsidiaries.2025-01-21This is an internal administrative update for BlackRock, Inc. to streamline its regulatory filing processes. It has no direct impact on Annexon Inc.'s corporate governance or operations.

Stakeholder Impact

  • Shareholders: May view the continued significant institutional ownership by BlackRock as a sign of stability and confidence in Annexon Inc.

Key Dates

DateDescription
2023-04-30Date of the previously revoked Power of Attorney for BlackRock, Inc.
2025-01-21Effective date of the new Power of Attorney for BlackRock, Inc., revoking the prior one.
2025-12-31Date of the event which required the filing of this statement, reflecting BlackRock's beneficial ownership.
2026-01-21Date of filing and signature for this Schedule 13G Amendment No. 1.

Keywords

Annexon Inc, BlackRock, Schedule 13G, beneficial ownership, common stock, institutional investment, ANXN

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