SCHEDULE: Opaleye Management Reports 13.3% Stake in Alpha Cognition

Opaleye Management Inc., Opaleye L.P., and James Silverman have jointly filed a Schedule 13G, reporting beneficial ownership of 2,895,107 shares of Alpha Cognition Inc. common stock, representing 13.30% of the class.

Summary

• Opaleye Management Inc., Opaleye L.P., and James Silverman have jointly filed a Schedule 13G, indicating their beneficial ownership of Alpha Cognition Inc. common stock.
• The reporting persons collectively own 2,895,107 shares, which constitutes 13.30% of the outstanding common stock.
• Opaleye Management Inc. acts as the investment adviser, while Opaleye L.P. is the fund holding the shares.
• James Silverman is identified as the controlling person of Opaleye Management Inc.
• The filing is an amendment, indicating a change in reporting status or holdings.
• The shares are held in a managed account over which the Adviser has shared voting and dispositive power.
• The total number of shares outstanding as reported by Alpha Cognition Inc. in its Form 10-Q filed on May 14, 2026, was 21,774,104.

Sentiment

Score: 5

Explanation: StockSavvy.ai views this as a neutral filing. It reports a significant ownership stake but provides no operational or financial performance data, making it purely informational regarding holdings.

Positives

• Significant ownership stake of 13.30% in Alpha Cognition Inc. by Opaleye Management and related entities.
• Clear disclosure of beneficial ownership and reporting structure.

Negatives

• The filing does not provide specific details on the exact nature of the 'managed account' or the reasons for the amendment.
• No forward-looking statements or financial performance data are included in this Schedule 13G filing.

Risks

• Potential for increased influence or activism by Opaleye Management due to their significant stake.
• The filing does not detail any specific risks associated with Alpha Cognition Inc. itself, as it is a Schedule 13G focused on ownership.

Future Outlook

This filing is a Schedule 13G, which reports beneficial ownership and does not contain forward-looking statements or company guidance.

Management Comments

• The filing should not be construed as an admission that any of the Reporting Persons is, for purposes of Section 13 of the Securities Exchange Act of 1934, as amended, the beneficial owner of any of the shares reported herein.

Industry Context

StockSavvy.ai notes that Schedule 13G filings are common for institutional investors and investment managers accumulating significant stakes in public companies. This filing indicates a substantial passive investment by Opaleye Management in Alpha Cognition Inc., a biotechnology or technology firm, given its typical focus areas.

Stakeholder Impact

• Shareholders: The significant stake held by Opaleye Management may influence future corporate actions or board composition.
• Management of Alpha Cognition Inc.: May need to engage with Opaleye Management regarding their investment strategy.
• Other Investors: This filing provides transparency on a major shareholder, aiding investment decisions.

Next Steps

• Opaleye Management Inc., Opaleye L.P., and James Silverman will continue to file amendments to Schedule 13G as required by SEC regulations.
• Alpha Cognition Inc. will continue its business operations as described in its other SEC filings.

Key Dates

Keywords

Schedule 13G, Alpha Cognition Inc., Opaleye Management Inc., Opaleye L.P., James Silverman, Beneficial Ownership, SEC Filing, Investment Adviser, Common Stock, Shareholder