Form 4: Opaleye Management Increases Stake in Alpha Cognition

Opaleye Management Inc. reported the acquisition of 7,685 shares of Alpha Cognition Inc. across three transactions in June 2026.

Summary

• Opaleye Management Inc. purchased a total of 7,685 shares of Alpha Cognition Inc. (ACOG) between June 11 and June 15, 2026.
• The shares were acquired at weighted average prices ranging from $5.9053 to $5.9896 per share.
• Following these transactions, the total beneficial ownership held by Opaleye, L.P. increased to 2,652,574 shares.
• An additional 90,000 shares are held by a separately managed account under the management of Opaleye.

Sentiment

Score: 7

Explanation: StockSavvy.ai views this as a positive signal, as it reflects continued capital commitment from a major shareholder.

Positives

• Increased investment by a 10% owner signals confidence in the company's long-term prospects.
• Consistent accumulation of shares over a multi-day period suggests a strategic increase in position size.

Negatives

• None identified in this filing.

Risks

• Market volatility affecting the value of the equity position.
• Concentration risk for the reporting entity regarding its investment in Alpha Cognition.

Future Outlook

Not applicable as this is a transaction disclosure filing.

Industry Context

StockSavvy.ai notes that institutional accumulation of shares in small-cap biotech or pharmaceutical firms like Alpha Cognition often precedes or follows significant corporate milestones or clinical updates, reflecting active portfolio management.

Comparison to Industry Standards

• The purchase activity is consistent with standard institutional investment behavior for firms maintaining a 10% ownership threshold.
• The use of weighted average pricing for multiple transactions is standard practice for institutional investors to minimize market impact.

Stakeholder Impact

• Shareholders may view the increased institutional stake as a vote of confidence in the company's direction.

Next Steps

• Continued monitoring of future Form 4 filings to track further accumulation or divestment by Opaleye Management.

Key Dates

Keywords

Alpha Cognition, ACOG, Opaleye Management, Insider Trading, Form 4, Beneficial Ownership