Form 4: Opaleye Management Boosts Alpha Cognition Stake

Opaleye Management Inc., a 10% owner and director, increased its indirect beneficial ownership in Alpha Cognition Inc. through recent stock purchases.

Summary

• Opaleye Management Inc., a 10% owner and director of Alpha Cognition Inc. (ACOG), reported an increase in its indirect beneficial ownership.
• On March 27, 2026, Opaleye, L.P. acquired 10,000 shares of common stock at a weighted average price of $5.0792 per share.
• On March 30, 2026, Opaleye, L.P. acquired an additional 1,850 shares of common stock at a price of $4.9873 per share.
• Following these transactions, Opaleye, L.P. indirectly beneficially owns 2,471,850 shares of Alpha Cognition Inc. common stock.
• An additional 90,000 shares are indirectly beneficially owned by a separately managed account for which Opaleye Management Inc. acts as portfolio manager.
• Opaleye Management Inc. disclaims beneficial ownership of the reported shares except to the extent of its pecuniary interest.

Sentiment

Score: 8

Explanation: StockSavvy.ai views this as a strong positive signal, as a significant institutional investor and director is increasing its stake, indicating confidence in Alpha Cognition Inc.'s future.

Positives

• A significant shareholder and director, Opaleye Management Inc., increased its stake in Alpha Cognition Inc., signaling confidence in the company's future prospects.
• The purchases were made at prices ranging from $4.9873 to $5.0909, indicating a belief that the stock is undervalued or has potential for appreciation at these levels.
• The total indirect beneficial ownership by Opaleye, L.P. now stands at 2,471,850 shares, representing a substantial commitment.

Risks

• Opaleye Management Inc. disclaims beneficial ownership of the shares reported except to the extent of its pecuniary interest, which could imply a nuanced view on direct control or liability.

Future Outlook

This filing does not contain specific forward-looking statements or guidance regarding Alpha Cognition Inc.'s future performance.

Management Comments

• Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Industry Context

StockSavvy.ai notes that insider buying, especially by a significant institutional investor and director like Opaleye Management, often signals a positive outlook on the company's future prospects or a belief that the stock is currently undervalued. This activity can be a strong indicator for other investors, particularly in the biotechnology or pharmaceutical sector where Alpha Cognition operates, as it suggests confidence in upcoming milestones or product development.

Comparison to Industry Standards

• Insider buying by a 10% owner and director is generally viewed as a strong positive signal, aligning with similar actions seen in companies like Moderna (MRNA) or BioNTech (BNTX) where key stakeholders increasing their positions often precede positive developments.
• While the volume of shares purchased (11,850 shares) is not exceptionally large in absolute terms, the consistent accumulation by a major institutional holder like Opaleye Management, which manages substantial assets, indicates a strategic long-term view.
• This contrasts with more speculative short-term trading often seen with smaller individual insider transactions.

Related Party Transactions

• Opaleye Management Inc., as a 10% owner and director, is considered a related party to Alpha Cognition Inc.
• The reported transactions involve the acquisition of common stock by entities managed by Opaleye Management Inc. (Opaleye, L.P. and a Managed Account).

Stakeholder Impact

• Shareholders: This insider buying could instill greater confidence among existing shareholders and potentially attract new investors, as it signals a positive outlook from a knowledgeable insider.
• Employees: A positive signal from a major investor might boost employee morale and confidence in the company's stability and future.

Key Dates

Recommendation

The consistent buying by a significant institutional investor and director, Opaleye Management Inc., suggests strong insider confidence in Alpha Cognition Inc.'s valuation and future prospects. This action often precedes positive company developments and indicates that the insider believes the stock is currently undervalued, making it an attractive entry point for investors.

Keywords

Alpha Cognition Inc., ACOG, Opaleye Management Inc., Insider Buying, Form 4, Beneficial Ownership, Stock Purchase, Director, 10% Owner, Equity Acquisition