Form 4: Opaleye Management Boosts Alpha Cognition Stake

Opaleye Management Inc., a 10% owner and director, increased its beneficial ownership in Alpha Cognition Inc. through recent common stock purchases.

Summary

• Opaleye Management Inc., a director and 10% owner of Alpha Cognition Inc. (ACOG), reported acquiring additional common stock.
• On February 26, 2026, 590 shares were purchased at a weighted average price of $5.985 per share.
• On February 27, 2026, an additional 3,638 shares were purchased at a weighted average price of $5.9915 per share.
• These purchases increased Opaleye's indirect beneficial ownership through Opaleye, L.P. to 2,288,638 shares.
• An additional 80,000 shares are beneficially owned indirectly through a separately managed account.
• The reported prices are weighted averages, with transactions occurring within a range of $5.975 to $6.00.

Sentiment

Score: 8

Explanation: StockSavvy.ai views this as a strong positive signal, as a significant insider and 10% owner increasing their stake typically reflects confidence in the company's future prospects and valuation.

Positives

• A significant insider and 10% owner, Opaleye Management Inc., increased its stake in Alpha Cognition Inc., signaling confidence in the company's future prospects.
• The purchases were made at prices ranging from $5.975 to $6.00, indicating a belief in value at or around current market levels.

Future Outlook

This filing does not contain specific forward-looking statements or guidance from Alpha Cognition Inc. management, but the insider buying activity by Opaleye Management Inc. may be interpreted as a positive outlook from a significant shareholder and director.

Management Comments

• Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Industry Context

StockSavvy.ai notes that insider buying, especially from a significant shareholder and director like Opaleye Management Inc., often signals internal confidence in a company's valuation or future performance. This activity for Alpha Cognition Inc. could be viewed positively by the market, suggesting that those closest to the company see potential upside.

Comparison to Industry Standards

• StockSavvy.ai observes that insider purchases, particularly by institutional investors holding board seats, are generally considered a strong bullish signal. While the volume of shares purchased (4,228 shares) is relatively small compared to Opaleye's total holding of 2,288,638 shares, the consistent buying at market prices suggests a continued belief in Alpha Cognition's value, aligning with a common pattern where insiders accumulate shares when they perceive undervaluation or strong future prospects, unlike passive index funds or short-term traders.

Related Party Transactions

• The reported stock purchases by Opaleye Management Inc. are considered related party transactions, as Opaleye is a director and 10% owner of Alpha Cognition Inc.

Stakeholder Impact

• Shareholders: Existing shareholders may view this insider buying as a positive indicator, potentially increasing confidence and demand for the stock.
• Management: The purchases by a director and significant owner could reinforce alignment between management and major investors.

Key Dates

Recommendation

The consistent buying by a significant insider and 10% owner, Opaleye Management Inc., suggests strong internal confidence in Alpha Cognition Inc.'s valuation and future prospects. This insider activity often precedes positive company developments or a re-rating of the stock, making it a compelling 'buy' signal for seasoned investors.

Keywords

Alpha Cognition Inc., ACOG, Opaleye Management Inc., Insider Buying, Form 4, Beneficial Ownership, Stock Purchase, Director, 10% Owner